- System of ultra-small sensors monitors and maps pressure changes along the blood-brain
barrier in laboratory animals
- Monitors changes in intracranial pressure throughout onset and progression of disease
- Enables medical professionals to identify a relationship between changes in intracranial
pressure and development of neurological disease
Disorders that occur in the nervous system affect millions of people every year.
These disorders include trauma, vascular diseases, and immunological diseases of
the nervous system. Many of these disorders produce changes in the blood-brain barrier.
The goal of this program is to develop a sensor system that can monitor small changes
in the blood-brain barrier to see what they can tell us about the relationships
of pressure to disease and injury.
This application, developed by Tufts and design and engineering firm Foster Miller,
is for animal research only. The sensor is mounted on a syringe tip to be inserted
into the blood brain barrier area. A hooked latch keeps the sensor at the correct
depth in the skull.
Source: Foster Miller and Tufts University
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